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male hormones

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A Japanese study of nearly 37,000 people, published in the online journal BMJ Open, said balding men were 32% more likely to have coronary heart disease.

However, the Japanese researchers said the risks were less than for smoking or obesity.

A shifting hairline is a fact of life for many men. Half have thinning hair by their 50s and 80% have some hair loss by the age of 70.

A Japanese study of nearly 37,000 people said balding men were 32 percent more likely to have coronary heart disease

A Japanese study of nearly 37,000 people said balding men were 32 percent more likely to have coronary heart disease

Researchers at the University of Tokyo sifted through years of previous research into links between hair loss and heart problems.

They showed that hair that went thin on the crown was associated with coronary heart disease. This was after adjusting for other risk factors such as age and family history.

However, a receding hairline did not seem to affect the risk.

Dr. Tomohide Yamada, of the University of Tokyo, said: “We found a significant, though modest, link between baldness, at least on the top of the head, and risk for coronary heart disease.

“We thought this is a link, but not as strong as many other known links such as smoking, obesity, cholesterol levels and blood pressure.”

He said younger men losing hair on the top of their head should focus on improving their lifestyle to ensure they keep their heart healthy.

However, Dr. Tomohide Yamada said there was not enough evidence to suggest screening bald men for heart problems.

Any explanation for the link is uncertain.

There are ideas about increased sensitivity to male hormones, insulin resistance and inflammation in blood vessels affecting both the heart and the hair.

One in five men and one in eight women dies of coronary heart disease which is caused by blood vessels that nourish the heart becoming blocked.

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An analysis of hundreds of years of eunuch “family” records showed that castration had a huge effect on the lifespans of Korean men.

They lived up to 19 years longer than uncastrated men from the same social class and even outlived members of the royal family.

The researchers believe the findings show male hormones shorten life expectancy.

The study is published in the journal Current Biology.

Castration before puberty prevents the shift from boy to man. One of the scientists involved in the study, Dr. Cheol-Koo Lee from Korea University, said: “The records said that eunuchs had some women-like appearances such as no moustache hair, large breasts, big hips and thin high-pitched voice.”

An analysis of hundreds of years of eunuch "family" records showed that castration had a huge effect on the lifespans of Korean men

An analysis of hundreds of years of eunuch "family" records showed that castration had a huge effect on the lifespans of Korean men

Eunuchs had important roles in many cultures from protecting harems to castrati superstar singing sensations. The imperial court of the Korean Chosun dynasty used eunuchs to guard the gates and manage food. They were the only men outside the royal family allowed to spend the night in the palace.

They could not have children of their own, so they adopted girls or castrated boys.

Researchers in South Korea analyzed the genealogical record of these “eunuch families”.

They worked out the lifespans of 81 eunuchs born between 1556 and 1861. The average age was 70 years, including three centenarians – the oldest reached 109.

By comparison, men in other families in the noble classes lived into their early 50s. Males in the royal family lasted until they were just 45 on average.

There are no records for women at the time for comparison.

Dr. Kyung-Jin Min, from Inha University, said: “We also thought that different living circumstances or lifestyles of eunuchs can be attributed to the lifespan difference.

“However, except for a few eunuchs, most lived outside the palace and spent time inside the palace only when they were on duty.”

Instead he thinks the data “provides compelling evidence that male sex hormone reduces male lifespan”.

Women tend to outlive men across human societies. However, theories are hard to test in experiments and the exact reason for the difference is uncertain.

One thought is that male sex hormones such as testosterone, which are largely produced in the testes, could be damaging. The researchers said the hormones could weaken the immune system or damage the heart. Castration would prevent most of the hormone from being produced, protecting the body from any damaging effect and prolonging lifespan.

Dr. Kyung-Jin Min said: “It is quite possible that testosterone reduction therapy extends male lifespan, however, we may need to consider the side effects of it, mainly reduction of sex drive in males.”