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genetic variation

A new study suggests that Neanderthals were already on the verge of extinction in Europe by the time modern humans arrived on the scene.

The study used DNA analysis which revealed most Neanderthals in Western Europe died out as early as 50,000 years ago – thousands of years before our own species appeared.

A small group of Neanderthals then recolonized parts of Europe, surviving for 10,000 years before vanishing.

The work is published in the journal Molecular Biology and Evolution.

An international team of researchers studied the variation, or diversity, in mitochondrial DNA extracted from the bones of 13 Neanderthals.

This type of genetic information is passed down on the maternal line; because cells contain multiple copies of the mitochondrial genome, this DNA is easier to extract from ancient remains than the DNA found in the nuclei of cells.

The fossil specimens came from Europe and Asia and span a time period ranging from 100,000 years ago to about 35,000 years ago.

The scientists found that west European fossils with ages older than 48,000 years, along with Neanderthal specimens from Asia, showed considerable genetic variation.

But specimens from western Europe younger than 48,000 years showed much less genetic diversity (a six-fold reduction in variation compared to the older remains and the Asian Neanderthals).

A new study suggests that Neanderthals were already on the verge of extinction in Europe by the time modern humans arrived on the scene

A new study suggests that Neanderthals were already on the verge of extinction in Europe by the time modern humans arrived on the scene

In their scientific paper, the scientists propose that some event – possibly changes in the climate – caused Neanderthal populations in the West to crash around 50,000 years ago. But populations may have survived in warmer southern refuges, allowing the later re-expansion.

Low genetic variation can make a species less resilient to changes in its environment, and place it at increased risk of extinction.

“The fact that Neanderthals in Europe were nearly extinct, but then recovered, and that all this took place long before they came into contact with modern humans, came as a complete surprise,” said lead author Love Dalen, from the Swedish Museum of Natural History in Stockholm.

“This indicates that the Neanderthals may have been more sensitive to the dramatic climate changes that took place in the last Ice Age than was previously thought.”

Neanderthals were close evolutionary cousins of modern humans, and once inhabited Europe, the Middle East and Central Asia. The reasons behind their demise remain the subject of debate.

The appearance of modern humans in Europe around the time of the Neanderthal extinction offers circumstantial evidence that Homo sapiens played a role. But changes in the climate and other factors may have been important contributors.

“The amount of genetic variation in geologically older Neanderthals as well as in Asian Neanderthals was just as great as in modern humans as a species,” said co-author Anders Gotherstrom, from Uppsala University.

“The variation among later European Neanderthals was not even as high as that of modern humans in Iceland.”

The researchers note that the loss of genetic diversity in west European Neanderthals coincided with a climatic episode known as Marine Isotope Stage Three, which was characterized by several brief periods of freezing temperatures.

These cold periods are thought to have been caused by a disturbance of oceanic currents in the North Atlantic, and it is possible that they had a particularly strong impact on the environment in Western Europe, note the researchers.

Over the last few decades, research has shown that Neanderthals were undeserving of their brutish reputation.

Researchers recently announced that paintings of seals found in caves at Nerja, southern Spain, might date to 42,000 years – potentially making them the only known art created by Neanderthals. However, this interpretation remains controversial.