Hillary Clinton made history by accepting the Democratic nomination at the party’s national convention in Philadelphia.
The former secretary of state has told voters the presidential election is a “moment of reckoning”.
Speaking on the final night of the Democratic convention, the first woman nominated by a major party said there were huge challenges.
Hillary Clinton accused her Republican opponent in November’s election, Donald Trump, of sowing discord.
“He wants to divide us – from the rest of the world, and from each other.”
Donald Trump tweeted that the speech had failed to address the threat posed by radical Islam, making Hillary Clinton unfit to lead the country.
Before taking the stage, Hillary Clinton’s daughter Chelsea shared personal memories of her mother.
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“My wonderful, thoughtful, hilarious mother,” she said.
Chelsea Clinton added: “She was always there for me.”
After embracing her daughter, Hillary Clinton delivered a speech which featured a stark admission about the threats to national unity.
“Bonds of trust and respect are fraying. And just as with our founders there are no guarantees. It truly is up to us. We have to decide whether we’re going to work together so we can all rise together.”
The former secretary of state and first lady added: “We are not afraid. We will rise to the challenge, just as we always have.”
The risk to American prosperity included inequality, limited social mobility, political gridlock, “threats at home and abroad” and frustration over wage stagnation, Hillary Clinton said.
However, the Democratic nominee was confident these challenges could be overcome with the American values of “freedom and equality, justice and opportunity”.
Hillary Clinton acknowledged that too many Americans had been “left behind” by economic forces and addressed them directly: “Some of you are frustrated – even furious. And you know what? You’re right.”
Another highlight at the convention on July 28 was when the father of a fallen Muslim soldier challenged Donald Trump over his Muslim ban, prompting an ovation.
General John Allen, former commander of US forces in Afghanistan, appeared on stage with other military veterans and gave Hillary Clinton a ringing endorsement as commander-in-chief.
Hillary Clinton’s high-stakes remarks on the closing night of the four-day convention followed a rousing speech by President Barack Obama.
Barack Obama said on July 27 there had never been a man or woman more qualified than Hillary Clinton to serve as president.
Hillary Clinton and Donald Trump are set for an election battle widely considered to be a tight race when voters head to the polls in November.
Hillary Clinton has announced Tim Kaine, a 58-year-old centrist senator from Virginia, as her running mate.
The Democratic presidential candidate broke the news in a tweet on July 22. She plans a formal announcement on July 23.
Hillary Clinton passed over more left-leaning candidates in favor of Tim Kaine, who is a strong supporter of free-trade agreements.
Tim Kaine’s home state of Virginia is a major battleground in the coming election.
He speaks fluent Spanish and could help the Clinton campaign maintain its support among Hispanic Americans – a growing voting bloc.
An experienced politician who has been toughly vetted, Tim Kaine is considered a “safe” choice for the vice-president slot. He personally opposes abortion but supports abortion rights.
Tim Kaine was a finalist to be Barack Obama’s running mate in 2008 and served as Virginia governor before his time in the Senate.
Hillary Clinton also reportedly interviewed liberal firebrand Senator Elizabeth Warren of Massachusetts and Senator Cory Booker, an African-American senator from New Jersey. Agriculture Secretary Tom Vilsack was said to have been on her shortlist.
Meanwhile, Donald Trump, in a text to his supporters, described President Barack Obama, Hilalry Clinton and Tim Kaine as “the ultimate insiders” and appealed to voters to not “let Obama have a third term”.
GOP chief Reince Priebus tweeted scornfully: “Hillary Clinton’s choice of Tim Kaine does nothing to unify a fractured Democrat base repelled by her dishonesty and cronyism.”
Democratic candidate Hillary Clinton has reached the required number of delegates for her nomination, an AP tally suggests.
The count puts Hillary Clinton on 2,383 – the number needed to make her the presumptive nominee.
Hillary Clinton will become the first female nominee for a major US political party.
However, rival Bernie Sanders said Hillary Clinton had not won as she was dependent on superdelegates who could not vote until July’s party convention.
Hillary Clinton reached the threshold with a big win in Puerto Rico and a burst of last-minute support from superdelegates, AP reported.
Superdelegates are party insiders who can pledge their support for a candidate ahead of the convention but do not formally vote for them until the convention itself.
At an appearance in Long Beach, California, shortly after the news broke, Hillary Clinton said: “We are on the brink of a historic and unprecedented moment but we still have work to do.
“We have six elections tomorrow and we’re going to fight hard for every single vote, especially right here in California.”
Voters will go to the polls for Democratic primaries on June 7 in California, Montana, New Mexico, North Dakota, South Dakota, and New Jersey.
The nominee for either party is not officially named until the parties’ respective conventions.
Bernie Sanders has vowed to stay in the race until the convention, and his campaign team said the Vermont senator would attempt to win back superdelegates who have pledged their support to Hillary Clinton.
His spokesman Michael Briggs said it was too early to call the Democratic contest.
“It is unfortunate that the media, in a rush to judgement, are ignoring the Democratic National Committee’s clear statement that it is wrong to count the votes of superdelegates before they actually vote at the convention this summer,” Michael Briggs said.
“Our job from now until the convention is to convince those superdelegates that Bernie is by far the strongest candidate against Donald Trump.”
Hillary Clinton, a former secretary of state, New York senator and First Lady, leads Bernie Sanders by three million votes, 291 pledged delegates and 523 superdelegates, according to AP’s count.
She has won 29 caucuses and primaries to his 21 victories – and an estimated 2.9 million more voters have backed her during the nominating process.
That gives Hillary Clinton a significantly greater lead over Bernie Sanders than Barack Obama had over her in 2008 – he led by 131 pledged delegates and 105 superdelegates at the point he clinched the nomination.