At least two Palestinians have been killed and 200 wounded in the West Bank during protests against Israel’s campaign in Gaza, officials say.
About 10,000 protesters marched from Ramallah towards East Jerusalem, where they were met by Israeli forces.
At least 15 people died and scores were injured when an UN-run shelter came under fire in Gaza on Thursday.
More than 800 Palestinians and 35 Israelis have died since the Israel-Hamas conflict began on July 8.
Palestinian leaders in the West Bank have called for a “day of anger” on Friday, one of the last days of Ramadan.
The protest at Qalandia, outside Ramallah, saw Israeli border police use “riot control measures” and live fire. Protesters also used live ammunition, Israel said.
At least two Palestinians have been killed and 200 wounded in the West Bank during protests against Israel’s campaign in Gaza
Large protests were also reported in Jerusalem on Thursday evening, after Israeli police prevented men under 50 from visiting the al-Aqsa mosque.
At least 20 protesters were arrested after they threw rocks at police, Israeli police said.
Israel launched its military offensive with the declared objective of stopping Hamas firing rockets into Israel.
It has since discovered a network of tunnels used by militants to infiltrate Israeli territory, and has vowed to destroy them to restore security.
Efforts to broker a ceasefire have been continuing despite the continued violence.
Reports suggest a deal under discussion could allow Israeli forces to remain in Gaza to destroy tunnels.
Palestinian leaders say this is the start of the “uprising of freedom and independence”. Thousands marched from the outskirts of Ramallah towards the Qalandia checkpoint calling for an end to the Israeli occupation.
Youths threw stones and petrol bombs towards the checkpoint and tried to destroy the barrier. Israeli police say they used percussion bombs and tear gas.
The demonstration was called for by a group of youths on Facebook, among them the son of the popular imprisoned Fatah leader Marwan Barghouti.
Palestinian President Mahmoud Abbas has urged Palestinians to expand the protests, and leaders in the West Bank have called for a “day of anger” on Friday.
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A UN shelter in northern Gaza was shelled on July 24, causing “multiple deaths and injuries,” according to a spokesman for the UN refugee agency.
At least 15 people have been killed and more than 200 injured when a UN-run school used as a shelter in Beit Hanoun, Gaza, was shelled, the Gaza health ministry says.
Hundreds of Palestinians were in the school in Beit Hanoun, fleeing heavy fighting in the area.
It is the fourth time that a UN facility has been hit in Israel’s offensive against Hamas militants.
In the past 16 days of fighting, more than 750 Palestinians and 32 Israelis have been killed, officials say.
In the past 16 days of fighting, more than 750 Palestinians and 32 Israelis have been killed
Israel launched its military offensive on July 8 with the declared objective of stopping Hamas firing rockets from Gaza.
Earlier on Thursday, UN humanitarian chief Valerie Amos said that it was “vital” to have a ceasefire.
“We have over 118,000 people now who are sheltering in UN schools… people are running out of food. Water is also a serious concern,” she said.
She said the conflict meant 44% of Gaza was a no-go area for Palestinians, and residents were running out of food.
Israel’s Prime Minister Benjamin Netanyahu said on Thursday he regretted each Palestinian civilian death, but said they were “the responsibility of Hamas”.
Correspondents say pools of blood lay on the ground in the courtyard of the school in Beit Hanoun in northern Gaza.
There was a large scorch mark where it appeared a shell had hit, the Associated Press news agency reports.
UN officials said that during the course of the day they had been trying to negotiate a window of time with the Israeli army for civilians to leave the area because of the heaving fighting.
Chris Gunness, a spokesman for the UN Relief and Works Agency for Palestine refugees (UNRWA), said it was never granted.
He said the Israeli army had been formally given the co-ordinates of the shelter in Beit Hanoun.
There has been no comment so far from the Israeli military.
Casualties from the attack have been taken to several local hospitals.
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