French President Francois Hollande and German President Joachim Gauck will commemorate the 100th anniversary of Germany’s declaration of war on France on August 3, 1914.
Francois Hollande and Joachim Gauck will make a joint tribute in Alsace to soldiers killed during World War One.
They will also lay the first stone for a memorial at Vieil Armand cemetery.
On Monday events will be held in Belgium to mark Britain’s declaration of war on Germany.
Some 30,000 men were killed in the mountains around Vieil Armand, known in German as Hartmannswillerkopf.
The cemetery there contains the remains of 12,000 unidentified soldiers.
Francois Hollande and Joachim Gauck will pay tribute to the sacrifice those men made and celebrate the importance of the modern Franco-German relationship in Europe.
They will lay the foundation stone for a Great War memorial and exhibition centre on the site, which is due to open its doors to the public in 2017.
Francois Hollande and Joachim Gauck will meet again on Monday in the Belgian city of Liege, where heads of state from across Europe will mark the escalation of the war after Germany invaded Belgium.