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BC-819, used to treat pancreatic cancer, is a double stranded DNA plasmid construct that incorporates the gene for diphtheria toxin (DTA) under the regulation of the promoter sequence for H19 gene.

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BioCancell has begun enrollment of phase IIb BC-819 pancreatic cancer clinical trial, while Halozyme has started randomized, controlled clinical trial with PEGPH20 in patients with advanced pancreatic cancer.   Tikcro Technologies Ltd. announced on October 6 that BioCancell, a clinical stage biotechnology company focused on developing targeted cancer therapies for solid cancer tumors, has co...

The life-extending medication should not be use as it shows no benefits for terminal cancer, and has dangerous side-effects, said the cancer experts.

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...ncet Oncology on September 26 . The study highlights the need of a judicious medication for terminal cancer patient.   Professor Richard Sullivan, of the King’s Health Partners Integrated Cancer Centre, London, has presented the study at the European Multidisciplinary Cancer Congress in Stockholm. Input from drug-makers, payers and educators will be key to future discussions, David Coll...

Much of terminal cancer therapy is "futile and potentially inconsistent with patients’ wishes", cancer experts say in Lancet Oncology.

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...ment strategy, especially the exclusion of the drugs that were expected to prolong life for terminal cancer patient.   A report on managing cancer costs, made by 37 cancer experts from developed countries, was published in the Lancet Oncology on September 26 . The study highlights the need of a judicious medication for terminal cancer patient. Professor Richard Sullivan has presented the stud...

Hereditary cancer study

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Zelboraf for metastatic melanoma approved by FDA   Prostate cancer: a new treatment option from Swedish Lund University researchers.   Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.   Telomere progressive shortening characterizes familial breast cancer     Medical scientists have found a new form of mechanism leading to hereditary...

"Microscopic image showing two T cells binding to beads, depicted in yellow, that cause the cells to divide. After the beads are removed, the T cells are infused into cancer patients." (Dr. Carl June / Pennsylvania Medicine)

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Zelboraf for metastatic melanoma approved by FDA.   Prostate cancer: a new treatment option from Swedish Lund University researchers.   Telomere progressive shortening characterizes familial breast cancer   [googlead tip="patrat_mediu" aliniat="stanga"]A new treatment for leukemia had amazing results, surprising even the researchers who designed it. The new treatment has eradicated the...

Abraxane, approved by FDA for breast cancer, could be a life-prolonging drug for patients with advanced pancreatic cancer.

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...ension) in combination with gemcitabine in 67 patients with previously untreated advanced pancreatic cancer were published in an online article by the Journal of Clinical Oncology.   Abraxane, approved by FDA for breast cancer, could be a life-prolonging drug for patients with advanced pancreatic cancer.   After the first phase of the study, the recommended Phase II dose was 125 mg/m2 of...

Researchers from Lund University have identified a method that may attack and destroy prostate cancer stem cells

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...nt post on the university website, the new therapy works by targeting a specific protein in prostate cancer stem cells. They found that the STAT3 protein is integral to the ability of stem cells to grow and regenerate. They also noted that the natural compound galiellalactone inhibits the activity of STAT3.   Prostate cancer that has become resistant to hormone treatment and that does not re...

Biscuits and cakes increase womb cancer risk by 42 percent

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...nacking regularly on biscuits or cakes can significantly increase women’s chances of developing womb cancer, a British study shows.   Women who eat biscuits or cakes two to three times a week were 33% more likely to suffer womb cancer than those who rarely served such sweets. Among those women indulging more than three times a week, the risk of developing womb tumors is increased with 42%. Ho...

Telomere chromosome

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...ce for telomere shortening as a mechanism of genetic anticipation, the successively earlier onset of cancer down generations. Mutations in two DNA repair genes, BRCA1 and BRCA2, characterize some, but not all, instances of hereditary breast cancer. Non-BRCA1/2 breast cancer families are heterogeneous, suggesting the existence of other genes conferring susceptibility. The group has investigated the...

Women who drank the most sweet soft drinks had a 78 percent increased risk of endometrial cancer

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...8,000 US women a year. “Other studies have shown increasing consumption of sugar-sweetened beverages has paralleled the increase in obesity. Obese women tend to have higher levels of estrogens and insulin than women of normal weight,” said Maki Inoue-Choi, who did the study while at the University of Minnesota and now is at the National Cancer Institute. It has to do with how insulin, which contro...

A new study suggests that one third of people diagnosed with throat cancer are infected with a form of the HPV virus

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...key proteins – E6. E6 knocks out part of cells’ protection system, which should prevent cancer developing. Having the antibodies means HPV has already overcome that defense and caused cancerous changes in cells. The researchers compared blood test results – some more than 10 years old – for 135 people who went on to develop throat cancer and for 1,599 cancer-free people. T...

Eating plenty of cereals and whole grains could reduce the risk of developing colorectal cancer, a study published in British Medical Journal says

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Eating plenty of cereals and whole grains could reduce the risk of developing colorectal cancer, a study published in British Medical Journal says. Scientists from Imperial College London found that for every 10 g a day increase in fibre intake, there was a 10% drop in the risk of bowel cancer. Researchers’ analysis of 25 previous studies found that fruit and vegetable fibre did not reduce...

Elizabeth Hurley signed the purchases from Estée Lauder Pink Ribbon Collection at Selfridges, to raise money for breast cancer awareness.

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...nts in its New York City race for breast cancer survivors. In 1993 Evelyn H.  Lauder launched Breast Cancer Awareness Month in the UK, she founded the Breast Cancer Research Foundation, co-creating the pink ribbon symbol. Elizabeth Jane Hurley, actress and model, is Estée Lauder’s Breast Cancer Awareness ambassador. She was married to Hugh Grant, actor. She has a child with  Steve Bing, film...

Swedish researchers at Karolinska Institute suggest there is a link between eating processed meat, such as bacon or sausages, and pancreatic cancer

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...ausage, every day would increase a person’s risk by 19%. But the chance of developing the rare cancer remains low. The World Cancer Research Fund suggested the link may be down to obesity. Eating red and processed meat has already been linked to bowel cancer. As a result the UK government recommended in 2011 that people eat no more than 70g a day. Prof. Susanna Larsson, who conducted the stu...

In the upcoming interview with Oprah Winfrey, Rihanna opens up about her relationship with Chris Brown

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In the upcoming interview with Oprah Winfrey, Rihanna opens up about her relationship with Chris Brown. And what Rihanna has to say about her ex-boyfriend, who was convicted of assaulting her three years ago, in the prerecorded interview will come as a surprise to some. Rihanna, 24, tells Oprah Winfrey: “I felt like the only person they hate right now is him. It was a weird, confusing space to be...

Angelina Jolie has preventative double mastectomy as she had an 87 percent chance of contracting breast cancer

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Angelina Jolie has revealed she has had a preventative double mastectomy after doctors estimated she had an 87% chance of contracting breast cancer. Angelina Jolie, 37, made the decision to undergo the procedure after learning that she is a carrier of the BRCA1 cancer gene. Her mother, Marcheline Bertrand, died at the age of 56 from ovarian cancer, which Angelina Jolie revealed she has a 50% chan...

Prostate cancer screening is performed by two methods: the digital rectal examination (DRE), and the prostate-specific antigen (PSA) blood test.

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...tate cancer risk. For every 5-point BMI increase, the risk to develop an aggressive form of prostate cancer is elevated with 9%. In the same time, for every 5-point BMI increase the risk to develop a less aggressive form of prostate cancer diminished with 6%. The study was published this month in the Annals of Oncology. Body mass index shows the relation between how many kilograms has a person and...

Eating cruciferous vegetables at least once a week can cut the risk of developing a variety of cancers

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...s sprouts, broccoli and cauliflower at least once a week can cut the risk of developing a variety of cancers. Those who ate them at least weekly cut the risk of mouth cancer and breast cancer by almost a fifth and oesophageal cancer by more than a quarter, a study has found. The research linked poor diet with the fatal disease with around a third of all cases of oral cancer is thought to be linked...

Fecal occult blood testing, flexible sigmoidoscopy and colonoscopy are the three main screening tests for colorectal cancer.

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...s target multiple markers to achieve high detection rates (DNA changes may differ between colorectal cancers) and very sensitive tests are required (DNA markers may be present in only trace quantities in stool). This type of test  has been shown to be more effective than fecal occult blood tests at detecting colon cancer and precancerous polyps. The first study was a large blinded investigation an...

A study of more than 16,000 women found those with a larger bra size were at greater risk of the disease

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...h breast size – three of which are strongly correlated with mutations already linked to breast cancer. Dr. Nicholas Eriksson said: “One of the variants is known to regulate the expression of the estrogen receptor gene which plays a vital role in breast growth and in the majority of breast cancer cases. “Another one of these mutations is located in a region of the genome that often shows abno...

Men who drank over seven cups of tea per day had a 50 percent higher risk of developing prostate cancer than moderate and non tea drinkers

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...y. Men who drank over seven cups of tea per day had a 50 percent higher risk of developing prostate cancer than moderate and non tea drinkers The study was led by Dr. Kashif Shafique of Glasgow University’s Institute of Health and Wellbeing. He said: “Most previous research has shown either no relationship with prostate cancer for black tea or some preventive effect of green tea. R...

PSA test should not be a routine in preventing prostate cancer, says US Preventive Services Task Force

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...growing that it wouldn’t have been fatal, even if left untreated. The overwhelming majority of cancers fall into the last group, the task force wrote: Fully 95% of men whose prostate cancers are detected with PSA tests will be alive 12 years later even if they don’t get treatment. And, the panel added, no study on prostate cancer screening has ever shown that screening reduces the numb...

Q-Cancer will allow doctors, nurses and pharmacists to quickly identify all known types of cancer while the patient waits

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...r, as it is known, will allow doctors, nurses and pharmacists to quickly identify all known types of cancer while the patient waits. It is hoped the device, which will also gauge the correct drug to prescribe cancer sufferers, will be used across the NHS within the next three years. The device has been invented as part of a partnership between private firm QuantuMDx, Newcastle University and Sheff...

Prostate cancer and vigorous exercise

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Exercise has beneficial influence on over 180 genes, including those that repair DNA and suppress tumor growth, and this might lead to prevention or delay of prostate cancer progression, a recent study shows. The findings of the new study will be presented on Friday at a meeting of the American Society of Clinical Oncology in San Francisco. These data should be viewed as preliminary until publish...

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Chris Brown has publicly announced he has dumped his girlfriend Karrueche Tran after being pictured with ex Rihanna for the third night in a row. Chris Brown, 23, admitted his close bond with Rihanna was the reason for the split, but stopped short of saying the exes had reconciled. He said in a statement: “I have decided to be single to focus on my career. I love Karrueche very much but I donR...