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BC-819, used to treat pancreatic cancer, is a double stranded DNA plasmid construct that incorporates the gene for diphtheria toxin (DTA) under the regulation of the promoter sequence for H19 gene.

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...tolerability and efficacy of gemcitabine combined with PEGPH20 in patients with advanced pancreatic cancer.   Halozyme Therapeutics, Inc., a biopharmaceutical company developing and commercializing products targeting the extracellular matrix for the diabetes, cancer, dermatology and drug delivery markets, announced on October 5 the commencement of patient dosing in a Phase 2 clinical trial w...

The life-extending medication should not be use as it shows no benefits for terminal cancer, and has dangerous side-effects, said the cancer experts.

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...side-effects, said the cancer experts.   “Special consideration must be given to costs of cancer care at the end of life. Many forms of cancer are currently incurable and patients will eventually die from their disease.” “In fact studies suggest that a substantial portion of the total cost of cancer care is for care delivered in the last weeks or days of life, and that much...

Much of terminal cancer therapy is "futile and potentially inconsistent with patients’ wishes", cancer experts say in Lancet Oncology.

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Campaigners disagreed with the report concerning terminal cancer patient treatment strategy, especially the exclusion of the drugs that were expected to prolong life for terminal cancer patient.   A report on managing cancer costs, made by 37 cancer experts from developed countries, was published in the Lancet Oncology on September 26 . The study highlights the need of a judicious medication...

Hereditary cancer study

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Zelboraf for metastatic melanoma approved by FDA   Prostate cancer: a new treatment option from Swedish Lund University researchers.   Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.   Telomere progressive shortening characterizes familial breast cancer     Medical scientists have found a new form of mechanism leading to hereditary...

"Microscopic image showing two T cells binding to beads, depicted in yellow, that cause the cells to divide. After the beads are removed, the T cells are infused into cancer patients." (Dr. Carl June / Pennsylvania Medicine)

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Zelboraf for metastatic melanoma approved by FDA.   Prostate cancer: a new treatment option from Swedish Lund University researchers.   Telomere progressive shortening characterizes familial breast cancer   [googlead tip="patrat_mediu" aliniat="stanga"]A new treatment for leukemia had amazing results, surprising even the researchers who designed it. The new treatment has eradicated the...

Abraxane, approved by FDA for breast cancer, could be a life-prolonging drug for patients with advanced pancreatic cancer.

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...ension) in combination with gemcitabine in 67 patients with previously untreated advanced pancreatic cancer were published in an online article by the Journal of Clinical Oncology.   Abraxane, approved by FDA for breast cancer, could be a life-prolonging drug for patients with advanced pancreatic cancer.   After the first phase of the study, the recommended Phase II dose was 125 mg/m2 of...

Researchers from Lund University have identified a method that may attack and destroy prostate cancer stem cells

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Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.   Zelboraf for metastatic melanoma approved by FDA.   Hereditary cancer: future methods of diagnosis and treatment   [googlead tip="patrat_mediu" aliniat="stanga"]Swedish researchers from Lund University have identified a new treatment method for the advanced prostate cancer that may attack and...

Biscuits and cakes increase womb cancer risk by 42 percent

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...nacking regularly on biscuits or cakes can significantly increase women’s chances of developing womb cancer, a British study shows.   Women who eat biscuits or cakes two to three times a week were 33% more likely to suffer womb cancer than those who rarely served such sweets. Among those women indulging more than three times a week, the risk of developing womb tumors is increased with 42%. Ho...

Telomere chromosome

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Prostate cancer: a new treatment option from Swedish Lund University researchers.  [googlead tip="patrat_mare" aliniat="stanga"] Zelboraf for metastatic melanoma approved by FDA.   Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.   Hereditary cancer: future methods of diagnosis and treatment   Progressive telomere shortening characterizes fami...

Women who drank the most sweet soft drinks had a 78 percent increased risk of endometrial cancer

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...g to a new study, women who drank the most sweet soft drinks had a 78% increased risk of endometrial cancer. Researchers have found that other sweet treats, such as baked goods, didn’t have an effect. Nor did natural fruit juice, even though it’s full of naturally occurring sugars. The findings fit in with other research linking sugar intake, obesity and a lack of exercise with the cancer, which k...

A new study suggests that one third of people diagnosed with throat cancer are infected with a form of the HPV virus

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A new study suggests that one third of people diagnosed with throat cancer are infected with a form of the HPV virus. HPV (human papillomavirus) is the major cause of cervical cancer. Actor Michael Douglas is reported to have spoken about the link after his own diagnosis with throat cancer. Experts said this study in the Journal of Clinical Oncology, which quantifies the link, showed “strik...

Eating plenty of cereals and whole grains could reduce the risk of developing colorectal cancer, a study published in British Medical Journal says

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Eating plenty of cereals and whole grains could reduce the risk of developing colorectal cancer, a study published in British Medical Journal says. Scientists from Imperial College London found that for every 10 g a day increase in fibre intake, there was a 10% drop in the risk of bowel cancer. Researchers’ analysis of 25 previous studies found that fruit and vegetable fibre did not reduce...

Elizabeth Hurley signed the purchases from Estée Lauder Pink Ribbon Collection at Selfridges, to raise money for breast cancer awareness.

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...the lights pink at the Selfridges Department Store in London as part of Estée Lauder’s Breast Cancer Awareness Campaign.   The Breast Cancer Awareness Month Event, held on September 29, changed the Selfridges’ signature from yellow to pink. The store, like the Empire State Building and Niagara Falls, was illuminated in pink to raise awareness to the importance of mammography scre...

Swedish researchers at Karolinska Institute suggest there is a link between eating processed meat, such as bacon or sausages, and pancreatic cancer

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...ute suggest there is a link between eating processed meat, such as bacon or sausages, and pancreatic cancer. Researchers said eating an extra 50g of processed meat, approximately one sausage, every day would increase a person’s risk by 19%. But the chance of developing the rare cancer remains low. The World Cancer Research Fund suggested the link may be down to obesity. Eating red and proces...

Prostate cancer screening is performed by two methods: the digital rectal examination (DRE), and the prostate-specific antigen (PSA) blood test.

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Recent studies emphasized the negative influence exerted by obesity on the risk to develop prostate cancer, the diagnostic and the recovery after surgical treatment. A meta-analysis of 25 prostate cancer studies over a 14 years period detailed the association between body mass index (BMI) and prostate cancer risk. For every 5-point BMI increase, the risk to develop an aggressive form of prostate...

Eating cruciferous vegetables at least once a week can cut the risk of developing a variety of cancers

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...s sprouts, broccoli and cauliflower at least once a week can cut the risk of developing a variety of cancers. Those who ate them at least weekly cut the risk of mouth cancer and breast cancer by almost a fifth and oesophageal cancer by more than a quarter, a study has found. The research linked poor diet with the fatal disease with around a third of all cases of oral cancer is thought to be linked...

Fecal occult blood testing, flexible sigmoidoscopy and colonoscopy are the three main screening tests for colorectal cancer.

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...s target multiple markers to achieve high detection rates (DNA changes may differ between colorectal cancers) and very sensitive tests are required (DNA markers may be present in only trace quantities in stool). This type of test  has been shown to be more effective than fecal occult blood tests at detecting colon cancer and precancerous polyps. The first study was a large blinded investigation an...

Angelina Jolie has preventative double mastectomy as she had an 87 percent chance of contracting breast cancer

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...a preventative double mastectomy after doctors estimated she had an 87% chance of contracting breast cancer. Angelina Jolie, 37, made the decision to undergo the procedure after learning that she is a carrier of the BRCA1 cancer gene. Her mother, Marcheline Bertrand, died at the age of 56 from ovarian cancer, which Angelina Jolie revealed she has a 50% chance of contracting. Writing in an editoria...

Prostate cancer and vigorous exercise

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...nes, including those that repair DNA and suppress tumor growth, and this might lead to prevention or delay of prostate cancer progression, a recent study shows. The findings of the new study will be presented on Friday at a meeting of the American Society of Clinical Oncology in San Francisco. These data should be viewed as preliminary until published in a peer-reviewed journal. “There are m...

Men who drank over seven cups of tea per day had a 50 percent higher risk of developing prostate cancer than moderate and non tea drinkers

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According to new research, men who are heavy tea drinkers may be more likely to develop prostate cancer. A team from Glasgow University tracked the health of more than 6,000 male volunteers over a period of 37 years. They found men who drank over seven cups of tea per day had a 50% higher risk of developing prostate cancer than moderate and non tea drinkers. The team said it did not know if tea w...

A study of more than 16,000 women found those with a larger bra size were at greater risk of the disease

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...h breast size – three of which are strongly correlated with mutations already linked to breast cancer. Dr. Nicholas Eriksson said: “One of the variants is known to regulate the expression of the estrogen receptor gene which plays a vital role in breast growth and in the majority of breast cancer cases. “Another one of these mutations is located in a region of the genome that often shows abno...

Q-Cancer will allow doctors, nurses and pharmacists to quickly identify all known types of cancer while the patient waits

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Q-Cancer, a groundbreaking device that can diagnose cancer in just 20 minutes, is being developed in the UK. The world’s first tumor profiler, as it is known, will allow doctors, nurses and pharmacists to quickly identify all known types of cancer while the patient waits. It is hoped the device, which will also gauge the correct drug to prescribe cancer sufferers, will be used across the NH...

PSA test should not be a routine in preventing prostate cancer, says US Preventive Services Task Force

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...t. They said the answer was no: “The vast majority of men who are treated do not have prostate cancer death prevented or lives extended from that treatment, but are subjected to significant harms.” PSA test should not be a routine in preventing prostate cancer, says US Preventive Services Task Force Dr. Michael LeFevre, a family medicine doctor at the University of Missouri School of...

The world is facing a "tidal wave" of cancer, and restrictions on alcohol and sugar need to be considered

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...to be considered The developing world will bear the brunt of the extra cases. The WHO’s World Cancer Report 2014 said the major sources of preventable cancer included: Smoking Infections Alcohol Obesity and inactivity Radiation, both from the sun and medical scans Air pollution and other environmental factors Delayed parenthood, having fewer children and not breastfeeding For most countri...

A study of almost 2,000 men found prostate cancer cases rose dramatically in those who often ate meat cooked in a pan, with red meat being particularly dangerous

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A couple of hamburgers a week could increase the chances of getting prostate cancer by 40%, according to new a research. Scientists say cooking meat at a high temperatures creates cancer causing chemicals that damage DNA. A study of almost 2,000 men found prostate cancer cases rose dramatically in those who often ate meat cooked in a pan, with red meat being particularly dangerous. Professor Mari...