HIV has ancient origins that could be traced back millions of years
A new research suggests that the origins of HIV can be traced back millions rather than tens of thousands of years.
HIV, which causes AIDS, emerged in humans in the 20th Century, but scientists have long known that similar viruses in monkeys and apes have existed for much longer.
A genetic study shows HIV-like viruses arose in African monkeys and apes 5 million to 12 million years ago.
The research may one day lead to a better understanding of HIV and AIDS.
The HIV virus affects 34 million people worldwide.
The disease emerged during the 20th century after a HIV like virus jumped from chimps to humans.
Scientists have long known that similar viruses, known as lentiviruses, are widespread in African primates.
Past genetic research has suggested these “cousins” of the HIV-virus arose tens of thousands of years ago, but some experts have suspected this is an underestimate.
Scientists at the University of Washington in Seattle, US, and the Fred Hutchinson Cancer Research Center, also in Seattle, looked at the genetic signatures of HIV-like viruses in a number of primates, including chimps, gorillas, orangutans and macaques.
Changes in genes that have evolved in the immune systems of monkeys and apes in Africa suggest the viruses arose between 5 and 16 million years ago.
The research, published in the journal PLOS Pathogens, gives clues to how the immune systems of our closest relatives evolved to fight infection.
Dr. Michael Emerman of the Fred Hutchinson Cancer Research Center said: “Our study reveals that, while primate lentiviruses may have modern consequences for human health, they have ancient origins in our non-human primate relatives.”
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